CHEM 3214 - Medicinal and Biological Chemistry III
North Terrace Campus - Semester 2 - 2016
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General Course Information
Course Details
Course Code CHEM 3214 Course Medicinal and Biological Chemistry III Coordinating Unit School of Physical Sciences Term Semester 2 Level Undergraduate Location/s North Terrace Campus Units 3 Contact Up to 9 hours per week Available for Study Abroad and Exchange Y Prerequisites CHEM 2510 & CHEM 2520 or equivalent Assumed Knowledge CHEM 3111 Assessment Exam, practical work Course Staff
Course Coordinator: Associate Professor David Huang
Course Timetable
The full timetable of all activities for this course can be accessed from Course Planner.
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Learning Outcomes
Course Learning Outcomes
1 Apply knowledge of synthetic bioorganic chemistry to the design of bioactive compounds. 2 Understand the mechanisms for biological activity and key biological reactions. 3 Understand the theory and importance of electron transfer in biological systems. 4 Describe the types of electron transfer centres and proteins that are commonly used to tightly regulate electron transfer in biology. 5 Explain the workings of the pharmaceutical industry. 6 Explain the design of protease inhibitors and their potential use as pharmaceuticals. 7 Interpret mass spectra to determine peptide and protein structure. 8 Undertake laboratory investigations using appropriate apparatus. 9 Conduct, analyse and interpret results of an experiment, and effectively communicate these in written reports.
University Graduate Attributes
This course will provide students with an opportunity to develop the Graduate Attribute(s) specified below:
University Graduate Attribute Course Learning Outcome(s) Deep discipline knowledge
- informed and infused by cutting edge research, scaffolded throughout their program of studies
- acquired from personal interaction with research active educators, from year 1
- accredited or validated against national or international standards (for relevant programs)
1-8 Critical thinking and problem solving
- steeped in research methods and rigor
- based on empirical evidence and the scientific approach to knowledge development
- demonstrated through appropriate and relevant assessment
1-7,9 Teamwork and communication skills
- developed from, with, and via the SGDE
- honed through assessment and practice throughout the program of studies
- encouraged and valued in all aspects of learning
8,9 Career and leadership readiness
- technology savvy
- professional and, where relevant, fully accredited
- forward thinking and well informed
- tested and validated by work based experiences
1-9 Intercultural and ethical competency
- adept at operating in other cultures
- comfortable with different nationalities and social contexts
- able to determine and contribute to desirable social outcomes
- demonstrated by study abroad or with an understanding of indigenous knowledges
8,9 Self-awareness and emotional intelligence
- a capacity for self-reflection and a willingness to engage in self-appraisal
- open to objective and constructive feedback from supervisors and peers
- able to negotiate difficult social situations, defuse conflict and engage positively in purposeful debate
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Learning Resources
Required Resources
There is no prescribed text for this course.
Recommended Resources
- ‘Organic Chemistry’ (Bruice, 5th Edition, Pearson Education, 2007)
- ‘Organic Chemistry’ (Clayden, Greeves, Warren and Wothers, Oxford University Press, 2001)
- ‘Inorganic Chemistry’ (Shriver & Atkins, 5th Edition, Oxford University Press, 2010)
- 'Inorganic Chemistry' (Housecroft & Sharp, 4th Edition, Pearson, 2012)
- ‘Physical Chemistry’ (Atkins, 8th Edition, Oxford University Press, 2006)
- ‘A Guide to Lasers in Chemistry’ (Van Hecke & Karukstis, Jones & Bartlett, 1998)
- 'Spectrometric Identification of Organic Compounds' (Silverstein, 7th Edition, Wiley Press, 2005)
- 'SI Chemical Data' (Aylward, 6th Edition, Wiley Press, 2007)
- ‘Modern Physical Organic Chemistry’ (Ansyln and Dougherty, University Science Books)
- Molecular Spectroscopy’ (Banwell, 4th Ed., McGraw Hill, 1994) out of print
All of these texts (except where noted) are available for purchase from UniBooks and all are available for loan from the Barr Smith library. Some are also available for consultation in the Chemistry Resource Centre (Rm 120, Johnson Laboratories).
References to other material and recent literature will be given in lectures.
Maths Resources
The Maths Learning Centre (MLC) helps all students learn and use the maths they need at uni. The MLC offers seminars, workshops, online, and print resources. It also run a drop-in room in Hub Central from 10am to 4pm Monday to Friday during teaching weeks. For more information, visit http://www.adelaide.edu.au/mathslearning/
For chemistry-specific maths help, visit http://www.adelaide.edu.au/mathslearning/resources/chem/Online Learning
MyUni: Teaching materials and course documentation will be posted on the MyUni website (http://myuni.adelaide.edu.au/).
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Learning & Teaching Activities
Learning & Teaching Modes
Lectures 12 x 2-hour sessions with one session per week
Practicals 8 x 6-hour sessions with one session per week
Tutorials 11 x 50-minute sessions with one session per weekWorkload
The information below is provided as a guide to assist students in engaging appropriately with the course requirements.
A student enrolled in a 3 unit course, such as this, should expect to spend, on average 12 hours per week on the studies required. This includes both the formal contact time required to the course (e.g., lectures and practicals), as well as non-contact time (e.g., reading and revision).
Learning Activities Summary
Coursework
Bioorganic Chemistry
Bioinorganic Chemistry
Medicinal Chemistry
Biological Structure Determination
Practicals
Practical exercises will provide students with "hands on" experience in the quantitative use of various analytical methods. In addition, students will be involved in the analysis of "real world" chemical samples.
Tutorials
Tutorials will be used to reinforce the concepts introduced in lectures through a combination of quantitative problem solving (what is present, and in what quantity), a discussion of the operational principles, including the strengths and weaknesses of various quantitative chemical methods, and consideration of appropriate possible solutions to chemical problems that have been identified through quantitative chemical analysis.Specific Course Requirements
Attendance is compulsory at all scheduled chemistry practical sessions. The learning outcomes for this course are substantially dependent on laboratory experience and practice. Therefore, missing any practical class in a semester will result in a grade of FAIL being recorded for the course. Students with medical or compassionate reasons for non-attendance will be given an opportunity to make up missed practical sessions. -
Assessment
The University's policy on Assessment for Coursework Programs is based on the following four principles:
- Assessment must encourage and reinforce learning.
- Assessment must enable robust and fair judgements about student performance.
- Assessment practices must be fair and equitable to students and give them the opportunity to demonstrate what they have learned.
- Assessment must maintain academic standards.
Assessment Summary
Assessment task Type of assessment Percentage of total assessment for grading purposes Hurdle (Yes/No) Outcomes being assessed Practical Formative & Summative 30% No 1-9 Exam Summative 70% Yes (45%) 1-7 Assessment Related Requirements
Practical work is compulsory – This includes attendance, conduct of required experimental work, attendance at demonstrator interviews (as required) and submission of laboratory reports. Practical work constitutes 30% of the total assessment.
To pass this course students must:
- Attend all practicals. If students do not meet the attendance requirement for practicals they will receive a Fail Grade. There is the opportunity for students to make up missed practicals.
- Attain a minimum of 45% for the exam:
Students who attain a final course grade of at least 45% but do not attain a minimum of 45% for the exam may be offered an Additional Academic Exam during the Replacement/Additional Assessment period, in line with the Modified Arrangements for Coursework Assessment Policy.
Assessment Detail
Examination
The end-of-semester examination will be based primarily on lecture/tutorial material. Students must sit the exam and achieve a minimum mark of 45% in order to pass the course.Practical
The laboratory course is worth 30% of your assessment at Level 3. Attendance at practical sessions is compulsory. If students do not meet the attendance requirement for practicals they will receive a Fail Grade. There is the opportunity for students to make up missed practicals.Submission
Submission of Assigned Work
Coversheets must be completed and attached to all submitted work. Coversheets can be obtained from the School Office (room G33 Physics) or from MyUNI. Work should be submitted via the assignment drop box at the School Office.Extensions for Assessment Tasks
Extensions of deadlines for assessment tasks may be allowed for reasonable causes. Such situations would include compassionate and medical grounds of the severity that would justify the awarding of a supplementary examination. Evidence for the grounds must be provided when an extension is requested. Students are required to apply for an extension to the Course Coordinator before the assessment task is due. Extensions will not be provided on the grounds of poor prioritising of time. The assessment extension application form can be obtained from: http://www.sciences.adelaide.edu.au/current/Late submission of assessments
If an extension is not applied for, or not granted then a penalty for late submission will apply. A penalty of 10% of the value of the assignment for each calendar day that is late (i.e. weekends count as 2 days), up to a maximum of 50% of the available marks will be applied. This means that an assignment that is 5 days or more late without an approved extension can only receive a maximum of 50% of the mark.Course Grading
Grades for your performance in this course will be awarded in accordance with the following scheme:
M10 (Coursework Mark Scheme) Grade Mark Description FNS Fail No Submission F 1-49 Fail P 50-64 Pass C 65-74 Credit D 75-84 Distinction HD 85-100 High Distinction CN Continuing NFE No Formal Examination RP Result Pending Further details of the grades/results can be obtained from Examinations.
Grade Descriptors are available which provide a general guide to the standard of work that is expected at each grade level. More information at Assessment for Coursework Programs.
Final results for this course will be made available through Access Adelaide.
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Student Feedback
The University places a high priority on approaches to learning and teaching that enhance the student experience. Feedback is sought from students in a variety of ways including on-going engagement with staff, the use of online discussion boards and the use of Student Experience of Learning and Teaching (SELT) surveys as well as GOS surveys and Program reviews.
SELTs are an important source of information to inform individual teaching practice, decisions about teaching duties, and course and program curriculum design. They enable the University to assess how effectively its learning environments and teaching practices facilitate student engagement and learning outcomes. Under the current SELT Policy (http://www.adelaide.edu.au/policies/101/) course SELTs are mandated and must be conducted at the conclusion of each term/semester/trimester for every course offering. Feedback on issues raised through course SELT surveys is made available to enrolled students through various resources (e.g. MyUni). In addition aggregated course SELT data is available.
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Student Support
- Academic Integrity for Students
- Academic Support with Maths
- Academic Support with writing and study skills
- Careers Services
- International Student Support
- Library Services for Students
- LinkedIn Learning
- Student Life Counselling Support - Personal counselling for issues affecting study
- Students with a Disability - Alternative academic arrangements
- YouX Student Care - Advocacy, confidential counselling, welfare support and advice
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Policies & Guidelines
This section contains links to relevant assessment-related policies and guidelines - all university policies.
- Academic Credit Arrangements Policy
- Academic Integrity Policy
- Academic Progress by Coursework Students Policy
- Assessment for Coursework Programs Policy
- Copyright Compliance Policy
- Coursework Academic Programs Policy
- Elder Conservatorium of Music Noise Management Plan
- Intellectual Property Policy
- IT Acceptable Use and Security Policy
- Modified Arrangements for Coursework Assessment Policy
- Reasonable Adjustments to Learning, Teaching & Assessment for Students with a Disability Policy
- Student Experience of Learning and Teaching Policy
- Student Grievance Resolution Process
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Fraud Awareness
Students are reminded that in order to maintain the academic integrity of all programs and courses, the university has a zero-tolerance approach to students offering money or significant value goods or services to any staff member who is involved in their teaching or assessment. Students offering lecturers or tutors or professional staff anything more than a small token of appreciation is totally unacceptable, in any circumstances. Staff members are obliged to report all such incidents to their supervisor/manager, who will refer them for action under the university's student’s disciplinary procedures.
The University of Adelaide is committed to regular reviews of the courses and programs it offers to students. The University of Adelaide therefore reserves the right to discontinue or vary programs and courses without notice. Please read the important information contained in the disclaimer.