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Unknown 40 = Apophysomyces elegans
Clinical presentation: The blistering on the medial aspect of the right foot was the first sign of infection.
![Clinical presentation](/mycology/sites/default/files/styles/ua_image_landscape/public/media/images/2021-09/unk40-1.jpg)
Direct microscopy: Tissue morphology in zygomycosis showing distinctive infrequently septate thin walled hyphae with focal bulbous dilations and irregular branching, typical for those species belonging to the Mucorales.
![Direct microscopy](/mycology/sites/default/files/styles/ua_image_landscape/public/media/images/2021-09/unk40-2.jpg)
Culture: Colonies are fast growing, white becoming creamy white to buff with age, downy with no reverse pigment, and are composed of broad, sparsely septate (coenocytic) hyphae typical of a zygomycetous fungus.
![Culture](/mycology/sites/default/files/styles/ua_image_landscape/public/media/images/2021-09/unk40-3.jpg)
Microscopy: Apophysomyces elegans showing distinctive funnel-shaped apophyses and a conspicuous pigmented sub-apical thickening below the apophysis.
![Microscopy](/mycology/sites/default/files/styles/ua_image_landscape/public/media/images/2021-09/unk40-4.jpg)
Comment: Apophysomyces elegans is a rare human pathogen usually associated with invasive lesions following traumatic implantation of the fungus through the skin. It is a soil fungus with a tropical to sub-tropical distribution.
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