Stratifying low-calorie sweeteners for type 2 diabetes risk (SWEET n SOUR)
About the study
The use of low-calorie (or “non-nutritive”) sweeteners has increased greatly in recent decades because they are perceived as healthy replacements for sugar. However, large population studies suggest that regular intake of these sweeteners can increase the risk of developing type 2 diabetes.
This study is designed to investigate whether different low-calorie sweeteners are more or less prone to affect blood glucose control. We will also test which sweeteners affect glucose absorption from the intestine, and whether they alter the types and amount of bacteria present in the intestine.
Eligible participants will be required to attend 4 sessions over 4 weeks period, 8am to 1pm approximately each.
Eligibility requirements
To be eligible for this study, you should be:
- In generally good health
- Aged 18 – 70 years
- Body mass index (BMI) 18 -30 kg/m2
Participants must be able to attend the Clinical Research Facility at the Adelaide Health and Medical Sciences Building on North Terrace.
Recruitment timeline
Start of recruitment: January 2023
End of recruitment: December 2027
Benefits
After successfully completing the trial, an honorarium of up to $320 will paid via EFT transfer to participants for their time.
