Our research program investigates how maternal nutrition and metabolic health influence reproductive outcomes across the continuum from preconception to offspring development. We integrate detailed dietary assessment with clinical reproductive outcomes in women undergoing assisted reproductive technologies, linking diet quality to different biological samples, and the impact on pregnancy success. Building on this, we examine how the gut microbiome interacts with diet to influence reproductive health, including in women with endometriosis, to identify modifiable pathways that may improve fertility outcomes. In parallel, we focus on gestational diabetes and metabolic dysfunction in pregnancy, developing and evaluating dietary strategies to improve maternal and neonatal outcomes.
Extending beyond pregnancy, we leverage large longitudinal cohorts, including the Australian Longitudinal Study on Women’s Health, and the Raine Cohort Study, to investigate how maternal lifestyles and pregnancy complications shape offspring health trajectories. Across all projects, we integrate dietary, clinical, and biological samples with advanced epidemiological and multi-omics approaches to identify mechanisms and inform targeted, translatable interventions that improve reproductive and long-term health outcomes.
