About ovarian cell biology and embryology
Our team of biomedical researchers is dedicated to advancing female reproductive health through fundamental discoveries in ovarian biology and early embryo development. Our work is uncovering the mechanisms by which a mature egg is ovulated from the ovary and the molecular events that enable fertilisation by sperm and healthy embryo development.
Using both animal models and human clinical samples, our basic science research is aimed at clinical questions, generating new knowledge with real-world applications. We are identifying how environmental conditions such as obesity, aging and toxicant exposure impact the sensitive biology of the ovary and egg, with consequences on fertility and offspring fitness.
On a cellular level, projects investigate mitochondrial biology, gene regulation, telomere reprogramming, cellular signalling and matrix remodelling. Our discoveries have applications for the development of infertility treatments for women, therapies for optimising animal reproduction and new contraceptives, as well as important implications for women’s health policies.
